Patients with personal MTC history or Multiple Endocrine Neoplasia type 2 (MEN2) syndromewhich includes familial MTCshould not use semaglutide, tirzepatide, or any GLP-1 compound
considerable interest exists in identifying these glucose-independent renoprotective actions Data from clinical trials suggest that GLP-1R agonists and, to a lesser extent, DPP-4 inhibitors marginally improve surrogate renal end points, plausibly beyond the effects of improved glycaemic control Abstract The gastrointestinal tract the largest endocrine network in human physiology orchestrates signals from the external environment to maintain neural and hormonal control of homeostasis
Now, one of the authors had a conflict of interest, affiliations with companies trying to commercialize thylakoid products, and you can see it in the spin
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