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In contrast, Ruminococcaceae UCG-009 was present in all experimental groups, and exhibited significantly greater relative abundance in both the LD control group and the 5A-1MQ-treated group switched from WD to LD compared to the WD control group (both significant before FDR correction

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19 (2): 1026 Capaccioli S, Nucci C, Quattrone A, et al

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Safety, tolerability, pharmacokinetics, and pharmacodynamics of cagrilintide with semaglutide for weight management: a Phase 1b trial