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Thyroid function tests (TSH and free T4) should be performed approximately 68 weeks after initiating or changing the dose of either medication , and then every 36 months once stable

After taking a 2.4 mg dose of semaglutide for 68 weeks (about 16 months), patient results showed a weight loss of 14.9% from baseline

These mechanisms contribute to the therapeutic benefits of GLP-1 based therapies in mitigating hepatic steatosis and improving overall lipid homeostasis [27, 29]

Genetic context does not replace medical evaluation, but it may help clarify whether your baseline response pattern aligns with population norms or whether additional assessment could be valuable

Semaglutide is typically recommended for individuals with a BMI of 27 or higher