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PINK1-mediated Drp1(S616) phosphorylation modulates synaptic development and plasticity via promoting mitochondrial fission

Compared to cytosolic NADK (cNADK), mitochondrial NADK (mNADK) has a distinctive feature that it can directly phosphorylate nicotinamide adenine dinucleotide (NADH) to generate NADPH to alleviate oxidative stress in mitochondria

The development of drug resistance in cancerous cells is a major cause of concern, as it not only leads to tumor recurrence but also perpetuates the cancer, resulting in poor patient survival

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It also explained when selenium supplements might make sense, which I discussed with my clinician