semaglutide for people without diabetes What if you could get the benefits of a GLP-1 medication — the needle, without the weekly injection, without the sting — simply by taking a pill? That is no longer The Potential of Semaglutide Once-Weekly

According to current study findings, the guideline from ADA 2023 has designated SGLT-2i and GLP-1 RAs as first-line drugs for T2DM patients with established ASCVD or high cardiovascular risk, and metformin is no longer recommended as first-line therapy for T2DM patients with high cardiovascular risk due to its neutral HF benefits

Pohl, H

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Single cell transcriptomics reveal trans-differentiation of pancreatic beta cells following inactivation of the TFIID subunit Taf4