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doi: 10.1016/j.biopha.2017.10.001 101 ParkYZhangJCaiL

Clinical studies have shown significant weight reduction in many patients when combined with medical supervision and lifestyle changes

true anaphylaxis is uncommon but documented with several biologic agents

Most patients report side effects peak in weeks 1 to 2, then diminish significantly

As expected, we observed that the loss-of-function mutant form of hHPN RS exhibited higher protein levels compared to the wild-type hHPN WT , both in serum and liver lysate