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Efficacy and safety of dulaglutide added onto pioglitazone and metformin vs

The appetite suppression these drugs create makes it difficult to eat enough protein to preserve muscle mass, and roughly 25% of weight lost on GLP-1 drugs comes from lean tissue on average, with some trials reporting up to 40%

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These findings are important because researchers discovered a link between whether people noticed changes in their taste and how much weight they lost

There appeared to be a treatment-related asymptomatic increase in median serum lipase activity with liraglutide compared with placebo, otherwise no clinically relevant treatment-related changes in safety laboratory measures were apparent