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These drugs also simultaneously decrease levels of an enzyme called DPP-4, which inactivates GLP-1

The following strategies are important for those trying to lose weight without a prescription: Eat breakfast Strive to make breakfast the largest meal of the day (or at least frontload your day as much as possible) Aim to eat at least one fibre-rich food at every meal Make olive oil a dietary staple Be mindful of the order that you eat foods in, consume protein and vegetables before carbohydrates Snack on nuts Chew your food Eat slowly While natural approaches to raising GLP-1 may not be as potent as medications, they provide a drug-free approach to weight loss and healthy eating.

Adequate protein supports energy levels and prevents the muscle loss that can accompany aggressive caloric restriction on GLP-1 therapy

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Hels et al