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Pre-existing risk factors : Individuals with established osteoporosis, previous fragility fractures, advanced age (particularly postmenopausal women), low baseline BMI, or those taking medications that affect bone metabolism (such as corticosteroids) may be more susceptible to bone density changes during weight loss
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Researchers at Mass Eye and Ear in Boston, Massachusetts, a Harvard Medical School teaching hospital, became motivated late last summer to look at whether todays highly sought-after weight-loss drugs might be associated with an increased risk of NAION, after three patients, all taking semaglutide, were diagnosed with the condition within the same week
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