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All records were from a primary prevention registry within the University of Pittsburgh Medical Center multihospital system, which includes over 35 hospitals and 400 outpatient clinics in Pennsylvania, Maryland and West Virginia

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This is substantiated by two large, randomized placebo-controlled trials, the Womens Health Initiative study 11 and the Heart and Estrogen/Progestin Replacement study 12 that found a significant reduction in the incidence of diabetes in women assigned to menopausal estrogen therapy, thus providing evidence for the antidiabetic action of estrogen in women

It may also reduce androgen signaling

Other types of birth control may still be effective with semaglutide as they do not involve the digestive system