Since chemotherapy-induced side effects are frequently also caused by mitochondrial ROS, such as cardiotoxicity or kidney injury after doxorubicin and cisplatin treatments, respectively, these potential redox therapies should be carefully directed to the target cells
system xc inhibition leads to a depletion of the vital antioxidant GSH
Last winter it was serendipitous that my old drivers license expired before Id had the chance to apply for one in our new state: For months, I took advantage of the reason to walk everywhere I needed to go
Formation of RSOH, RSSG and RSSG can be transient and reversible, allowing these species to participate in biochemical functions, such as redox sensing and responding, catalysis, and signal transduction [11]
Gibco) at 37 C and 5% carbon dioxide