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The research on this molecule spans decades and hundreds of studies

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doi: 10.1186/s13073-017-0490-5 34 HijovE.BertkovI.tofilovJ

The activation of YAP subsequently induces extracellular matrix (ECM) deposition through enhanced secretion of connective tissue growth factor (CTGF), while concurrently promoting the production of fibrous collagen and connective tissue by the surrounding fibroblasts