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Nrf2-Related Signaling Pathway The nuclear factor erythrocyte 2-associated factor 2 (Nrf2) pathway is a major intracellular antioxidant stress pathway that plays an important role in oxidative stress response, cytoprotection and anti-inflammation in cells

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As an exception, in AML which is a blood cell cancer, NAD + did not correlate with any other redox metabolites, potentially because of high number of white blood cells (Fig