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Due to the challenges inherent in the identification of patients who might benefit most from mecasermin treatment, it may be helpful to engage a panel of clinical experts to inform treatment decisions, at least when the diagnosis cannot be confirmed

Liraglutide has been shown to halt the progression of steatosis and is associated with the induction of autophagy via activation of AMPK and suppression of mTOR pathways (He et al., 2016)

While many patients report improved mood and mental clarity, some experience negative side effects such as anxiety, depression, and cognitive issues like brain fog

Second, improved insulin sensitivity may indirectly affect iron regulation