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Molecular docking As no experimentally resolved structure was available, the amino acid sequence of mouse PCBP1 (GeneID: 23983) was modeled using ProteinX, an open-source AlphaFold-like implementation, and the resulting structure was refined with Rosetta Relax to improve stereochemical quality and stability

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The hHPN RS mutant was engineered to produce hepsin without functional activity by introducing two specific mutations in critical regions of its proteolytic activity

Nat Rev Clin Oncol 14(1):1131 Martnez-Reyes I, Chandel NS (2020) Mitochondrial TCA cycle metabolites control physiology and disease

It helps accelerate elimination of fats and reduces obesity