The evolutionary origin of the PPP is ancient, possibly dating back to the prebiotic world [19]
Metabolism-based treatments such as the high-fat ketogenic diet and its variants can help to restore metabolic homeostasis and enable seizure control
For instance, thyroid cancer is associated with the increased presence of Clostridiaceae , Neisseria , and Streptococcus , whereas in patients with thyroid nodules, a relative increase of Streptococcus and Neisseria compared to healthy controls was observed (235)
36,37 The etiology again is thought to include altered SAM metabolism in patients with chronic liver disease regardless of the stage or cause of the disorder
These benefits highlight its potential use for those seeking alternative or additional recovery methods, though more clinical trials are needed to substantiate these claims fully