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Beyond diabetes and obesity, GLP-1s have also emerged as a longevity drug class with research showing potential benefits across inflammation, cardiovascular risk, liver fat reduction, and kidney protection

It may still act locally in the gut, through metabolites, or through microbiome-related pathways

MariTide: GI adverse events were the most common, including nausea, vomiting, and constipation

Stick with the 4-week timeline at 2mg, then escalate to 4mg as planned

Most of the data out there is from the heat stress itself, like your heart rate's elevating when you're in there, you're feeling hot, you're getting that cardiovascular