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Taken together, these data provide further understanding into the regulation of CBS and in particular into the genetic relationship between DYRK1A and CBS through the Akt/GSK3 and NF-B pathways, which should help develop more effective therapies to reduce cognitive deficits in people with DS

26 , 1690.e11690.e4 (2020)

B12 Deficiency and Weight Gain Although researchers are not certain why higher vitamin B12 levels are associated with a reduced risk of obesity or being overweight, they have a few theories

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