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Elevated CHAC1 expression in LUAD correlates with aggressive tumor progression and poor patient prognosis ( CHAC1 upregulation marks advanced disease states ( CHAC1 upregulation in renal cell carcinoma (RCC) is linked to advanced tumor stage and higher histological grade, suggesting its role in cancer progression and malignancy ( The elevated CHAC1 expression in LUAD promotes tumor proliferation and metastasis by enhancing glycolysis, lactate production, and ATP generation through regulation of pyruvate kinase M2 (PKM2)

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The percentage of hemoglobin forms was calculated from the optical density of characteristic peaks at 560, 577, 630, and 700 nm using millimolar extinction coefficients 65

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Extensive clinical data support short-term symptom control in acute injuries, with effects observed within hours to days