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Animals (n=6/each group) were categorized into group 1 (sham-control of F344 rat), group 2 (sham-control of DPP4-deficiency rat), group 3 [AHS by right cerebral injection of autologous blood (100 L) in F344 rat], group 4 (AHS + sitagliptin/600 mg/kg 3 h prior to and at 3 h then once per day after AHS) and group 5 (AHS in DPP4-deficiency rat)

In the unadjusted cause-specific-hazard regression model there was no difference in the risk of suicide or suicide attempts between patients treated with GLP-1 RAs compared with patients treated with SGLT-2 inhibitors or DPP-4 inhibitors, respectively, after 1 year and 3 years of follow-up, see Table 2

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How Long Does a GLP-1 Weight Loss Plateau Usually Last