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While Phase II trials in heart failure and primary mitochondrial myopathy did not meet primary efficacy endpoints, the TAZPOWER trial in Barth syndrome demonstrated significant improvements in muscle strength and sixminute walk distance, leading to FDA accelerated approval in 2025 [3][10]

doi: 10.1097/01.gco.0000193003.58158.4e

Research indicates that glycine may be a helpful therapy for schizophrenia, but some small studies (on high-dose glycine) showed a possibility that it may interact with these medications

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Improve markers linked to cardiovascular risk Better appetite control by targeting two hormones, making it easier to stick to a balanced diet