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doi: 10.1007/s12031-016-0714-y 181

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Your body uses glutathione to "clean up" cellular waste, so the more waste there is, the more glutathione you may need

CSD is associated with significant cerebral vasoconstriction (13), which triggers neuronal swelling and activation of meningeal trigeminal nerve endings and the trigeminal vascular system, ultimately contributing to migraine development (1416)