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Tesofensine Side Effects Because tesofensine acts as a central nervous system stimulant, its side effects tend to be stimulant-related: Dry mouth reported by 3040% of participants in clinical trials Insomnia difficulty falling or staying asleep, particularly if taken later in the day Increased heart rate mean increases of 58 beats per minute were observed in trials

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Do not take it with any other drink except a small glass (less than 120mL) of plain water

Most state Medicaid programs cover GLP-1 medications when prescribed for Type 2 diabetes, but coverage for obesity or weight loss is far less consistent

This makes the GCGR component particularly relevant for research into non-alcoholic fatty liver disease (NAFLD) models and energy balance studies