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[4] Based on animal research, it is thought that the increased methylmalonyl-CoA hydrolyzes to form methylmalonate (methylmalonic acid), a neurotoxic dicarboxylic acid, causing neurological deterioration

The treatment is commonly used in integrative medicine practices for individuals seeking improved energy, skin clarity, cognitive performance, and metabolic function

Real-time PCR was performed on ABI Stratagene Mx3000P instrument (Agilent Technologies, Santa Clara, CA, USA) using a TB Green Premix Ex Taq II (Takara Biomedical Technology, Beijing)

Zelles L, Stepper K, Zsolnay A

New insights into the mechanisms of the ketogenic diet