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This bypasses the GI tract entirely, which is the whole point: it's designed for people whose digestive system can't absorb B12 reliably

[2] For this reason, elevated serum homocysteine over 15 micromol/L and methylmalonic acid (MMA) over 0.271 micromol/L are considered better indicators of B 12 deficiency, rather than relying only on the concentration of B 12 in blood

Thus, the glycocalyx has become a potential therapeutic target for cardiovascular disease (39)

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