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(Basel) 16 (6), 967 (2021)

The client is encouraged to assume increasing participation in self-care activities

Crucially, this signaling is bidirectional: central neuroendocrine outputs (e.g., via autonomic nerves and the HPA axis) reciprocally modulate gut physiologyaltering intestinal transit time, mucus secretion, and nutrient availabilitythereby reshaping the microbial metabolic environment and SCFA production capacity

Reduce dose and monitor closely if: Headaches persist beyond two weeks at starting doses

In chronic wounds and mucosal infections, a dysbiotic microbial environment supports the growth of virulent, biofilm-producing organisms while suppressing beneficial commensals