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Mimics the natural pulsatile release pattern your pituitary uses

Placebo- and Exenatide-Controlled Trial (Add-on to Metformin and Thiazolidinedione) In this placebo-controlled trial with primary endpoint at 26 weeks, 976 adult patients were randomized to and received placebo, TRULICITY 0.75 mg once weekly, TRULICITY 1.5 mg once weekly, or exenatide 10 mcg BID, all as add-on to maximally tolerated doses of metformin (1500 mg per day) and pioglitazone (up to 45 mg per day)

Changes in the content of the intestinal mucus may be a factor in IBDs unbalanced immune response activation (Xavier and Podolsky 2007)

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Other reactions: Some individuals report transient headache, dizziness, flushing, or acneiform eruptions following injection