Reviews describe regenerative and protective actions, roles in skin regeneration, and modulation of multiple cellular pathways but this is largely mechanistic and preclinical work, not large human efficacy trials
doi: 10.1016/j.redox.2024.103460 259 JiwaHXieZQuXXuJHuangYHuangXet al
In the rodent studies reported to date it has generally been described as tolerated across the dose ranges examined, but comprehensive controlled human safety data do not exist, so conclusions about tolerability in people remain unconfirmed
INTRODUCTION Despite being considered one the safest pharmaceuticals, paracetamol/acetaminophen (N-acetyl-p-aminophenol, APAP) overdose is one of the most important causes of drug-induced liver injury, that can eventually lead to acute liver failure (ALF) ( 1, 2 )
Fibroblast cultures were divided into control conditions and peptide-exposed conditions