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A 2025 study by Streck and colleagues evaluated using ecigarettes versus conventional nicotine replacement therapy (cNRT) in adults with SUDs and found both options were safe and well toleratedthough the study did not directly assess SUD recovery outcomes

Most cancers have unique pathways leading to their progression, but nicotine contributes to both the development and progression of different cancers in several ways

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Variants at the 15q25 locus have been confirmed by several studies associated with increased tobacco addiction and lung cancer risk [47, 48], but a significant gene-environment interaction is controversial [50, 51]

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