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The Timeline: How Fast Weight Loss Happens with GLP-1 First Month: Initial Changes During your first four weeks on GLP-1 medication, your body enters an adjustment phase

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GLP-1 agonists were originally approved to treat Type 2 Diabetes (T2D) but their most recent incarnations, which consist of both next generation GLP-1s and combinations (Ozempic, Mounjaro, Wegovy, Zepbound), have moved beyond the realm of T2D into the treatment of obesity

7,33,34 Since that time, however, the study design, interpretation of results, and reporting of results from the UKPDS have been criticized, particularly because tight glycemic control did not result in fewer cardiovascular events or lower mortality in the primary analysis