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These early cues are easy to dismiss but important to catch

They found five different mutational "signatures" in the smokers, they reported in the journal Science

Gurgling pipes are most commonly caused by the tobacco being too moist, which can be easily remedied by letting the tobacco dry before lighting

Risk was higher among smokers who began before age 15 compared to those who began at older ages, and the risk was highest of all for those who began smoking before age 10

However, studies of socio-demographic correlates of smoking and smoking cessation rarely consider the role of mental illness and its relationship to both smoking and socio-economic status