The epoxide diol from benzo[a]pyrene is particularly dangerous because the large flat portion of them molecule likes to slide inbetween the bases of double stranded DNA (a process called intercalation), facilitating attack by nucleophilic sites on DNA at the electrophilic epoxide
This figure does not distinguish between those who quit smoking cold turkey and those who used NRT
A limitation was the brief follow-up and the inclusion of youth with a history of smoking, which treated ever smoking as a covariate and baseline current smoking frequency as a moderator rather than eliminating baseline ever-smokers from the analysis to prevent reverse causation
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Military, animal and bird sets were also popular, while the series, Views of Victoria in 1857 by S.T
