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In the European Union, the Tobacco Products Directive remains the cornerstone of e-cigarette regulation

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They consist of a few key ingredients: a base liquid, nicotine, flavorings, and optionally, additives

Provenance: Tiffany & Co., New York

Animal study Male C57BL/6 mice ranging from 8 to 12 weeks of age were purchased from the Jackson Laboratory (Bar Harbor, ME) and exposed to 4 non-filtered cigarettes (University of Kentucky research cigarettes, Lot number 1R5F), 5 days per week, for a total of 6 months