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Similarly, both a larger sample size and longer follow-up would have resulted in a higher number of cardiovascular events, perhaps allowing differences to be observed between persistent and non-persistent subjects

A meta-analysis of randomized controlled trials evaluating GLP-1 receptor agonists in PCOS women with obesity confirmed that these medications significantly reduce BMI, waist circumference, serum triglycerides and total testosterone

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These insights may support a more informed conversation with your provider about which medication class or program aligns with your genetic profile, though genetics does not predict exact medication response