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[24] Role in cell signaling [edit] Although best known for their ability to conjugate xenobiotics to GSH and thereby detoxify cellular environments, GSTs are also capable of binding nonsubstrate ligands, with important cell signaling implications

The WT mice had considerably less DNA adducts (molecules that are strongly bonded to DNA that can lead to DNA breaks and mutations) than the KO mice

AAPS PharmSciTech 23(6):179

2g) was attributed to pH-induced de-shielding of PEG and hydrophilic transition of thioether to sulfoxide, inducing the disassembly of the nanoparticles