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Conclusion Using the promoter gcvBp , a promoter involved in the glycine cleavage pathway that becomes activated when glycine levels are increased, we successfully designed a glycine biosensor by combining this promoter with an RFP reporter

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Part of the images was generated by BioRender ( and GEPIA2 ( We also appreciate the technical support from Core Utilities of Cancer Genomics and Pathobiology of the Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong