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Heme oxygenase-1 gene ablation or expression modulates cisplatin-induced renal tubular apoptosis

We want to be upfront with you: the evidence varies considerably

Think of it as a checklist they go through

We, therefore, considered an autocatalytic cycle in which GSSH reduces radicals to form perthiyl radicals (GSS), which recombine to form glutathione tetrasulfide (GSSSSG), which is then reduced by GSH to regenerate GSSH (Fig