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ALA acts as a potent antioxidant, helping to neutralize oxidative stress and support endothelial repair

Chromatographic and mass spectrometric parameters of this screening method are summarized in the Table 1

PMID 10855708

Although uterine expression levels of estrogen receptor , G protein-coupled estrogen receptor, and steroid synthase were upregulated in the high-dose group, the decreased expression of connexin 43 and alkaline phosphatase as well as the increased expression of insulin-like growth factor-binding protein three and monoamine oxidase were consistent with decreased estrogen signaling and lower uterine weights

Notably, Fento-1 exhibited a residual toxicity that ferroptosis inhibitors could not fully overcome, which reflects the potency of Fento-1