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S3E), and primary lung tumor cells from KP;Ddx3x fl/y mice (Fig

Semaglutide is the most extensively studied GLP-1 receptor agonist a single, highly selective incretin-pathway agonist that has become the reference standard against which newer dual and triple agonists are measured

These sources suggest a need for cautious use but do not provide conclusive evidence of significant adverse interactions

Studies indicate potential roles in neurodegenerative and oncologic diseases, where GLP-1 signaling can inhibit aberrant cell proliferation and promote apoptosis

The reason they are interesting for PMOS is simple: many women with PMOS have insulin resistance