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(6) Rapid tachyphylaxis: Continued tyramine exposure depletes releasable NE stores and replaces NE with pharmacologically weak false neurotransmitter stores, leading to diminished responsiveness despite ongoing tyramine presence

Hypersensitivity to Cobalt or Vitamin B12 Components If youre allergic to cobalt or parts of vitamin B12, be cautious

Adams C, Kopp M, Larburu N et al (2019) Structure and molecular mechanism of ER stress signaling by the unfolded protein response signal activator IRE1