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Understanding that architectural difference multi-molecule combination versus multi-target single molecule is the key to understanding how these three relate and why a researcher might choose one over another

16611663 For example, lower socioeconomic status has been associated with increased risk of developing DKA in T1D 1664 and diabetic retinopathy in T2D

Patients at higher risk for dehydration complications include older adults, individuals with chronic kidney disease, those taking diuretics or other medications affecting fluid balance, and patients with diabetes who may have underlying autonomic dysfunction affecting thirst perception