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While some clinical investigations indicate that combination therapy primarily exhibits gastrointestinal-related adverse effects without significant escalation in overall adverse event incidence 14,15 , contrasting expert opinions advocate for metformin dose reduction or discontinuation during GLP-1 receptor agonist treatment 16

Xiao, H., Gu, Z., Wang, G., & Zhao, T

Glapp was built by a GLP-1 user and health-tech professional who lived the experience firsthand

Originally developed for glycemic control in type 2 diabetes, GLP-1 receptor agonists are now prescribed for weight loss in non-diabetic populations