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[PubMed] [Google Scholar] 300.Waterhouse RN

10.1097/WNR.0b013e3282f50c66 23 Fuentes-SantamaraV.AlvaradoJ

When a persons blood sugar rises, GLP-1 tells the body to make more insulin to lower blood sugar

The glucagon component can transiently raise blood glucose before the GLP-1 and GIP components bring it back down

Some plans have implemented this by 2025 to negotiate better prices: they put certain expensive drugs (say certain brand biologics where they got a discount) on a Preferred Specialty tier at 25% coinsurance, and others on a higher tier at 33%