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3.3 Ruthenium compounds Cisplatin and other platinum(II)-based antitumor drugs are widely recognised for the treatment of various types of cancer, primarily ovarian, testicular, and lung cancer

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Current gene therapy research aims to target, for example, upstream targets of the GSH system or molecules associated with it (such as Nrf2, GPX, SLC7A11), genes aberrantly expressed in myocardial injury, and noncoding RNAs regulating mRNA transcription [76, 202, 250253]