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This test should be used in conjunction with serum B12 and MMA and not as a sole measurement (11, 12)

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Interestingly, the oocyte maturation was blocked at a very specific development stage (metaphase I arrest) where a sensor for DNA damage (Spindle Assembly Check point/Dna Damage Response) assesses the DNA integrity and blocks the oocyte maturation through the activation of a protein (ATM kinase)

This article systematically examines the dual role of ROS in the initiation, progression, and treatment resistance of breast cancer and explores innovative therapeutic strategies targeting ROS-related PCD

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