What to expect after switching Typical weight loss trajectory After switching to tirzepatide, you might notice: Continued weight loss if semaglutide had plateaued Potentially faster or greater weight loss than you experienced on semaglutide More consistent progress toward your weight goals Tirzepatide works best over long periods of time
However, this guidance may vary, especially if you already have diabetic retinopathy or other conditions
In one study, people taking Mounjaro lost significant weight over 72 weeks
In the past five years, research has found that GLP-1 drugs can lower the risk of a number of obesity-related chronic diseases such as heart disease, chronic kidney disease, sleep disorders, osteoarthritis and even certain cancers, with one study finding that people taking GLP-1 drugs had a lower risk of developing 42 different diseases than those given their usual medicines
They also received counseling every four weeks to support a reduced-calorie diet and increased physical activity