2 The chemosensitization effect of QUE in cancer chemotherapeutic The mechanisms of chemotherapeutic drugs are complex and include effects on DNA structure, inhibition of nucleic acid synthesis, DNA replication, and interference with mitotic tubulin ( 2.1 5-Fluorouracil 5-FU is a metabolic inhibitor that interferes with nucleic acid metabolism by inhibiting cancer cells thymidylate synthase (TS) activity, blocking their DNA synthesis, and inhibiting their proliferation
Once the seal is broken, chain-of-custody and sterility cannot be verified
Biochem J 1923;17(4-5):586-592
The most commonly cited starting protocol in the medical literature and clinical practice involves 250 micrograms administered once daily for acute injury, stepping up to 500 micrograms daily if response is insufficient after one to two weeks
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