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7,8,10 These phenotypes correlate with the transcriptional signature for stemness, such as high ALDH1A1 and aldehyde dehydrogenase activity, the expression of stem-related genes, and CD133 positivity

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108, 346349.10.1016/0304-3940(90)90665-V 189 OffenD.ZivI.SterninH.MelamedE.HochmanA

Furthermore, 2 weeks of subcutaneous infusion of nesfatin-1 improves glucose tolerance and insulin sensitivity in chow-fed and HFD-fed mice 227 , likely due to the direct action of nesfatin-1 on beta cells and not gutbrain signaling, similar to other peptides, such as GLP-1 and CCK 227,233,234